Brazil is the first country that started the distribution of the preventive treatment after a succesful launch event. On 4 March 2020 NHR Brasil and NLR hosted the official start of the innovative project ‘PEP++: Stop the Transmission of Leprosy!’ Political leaders from federal, state and district levels, as well as representatives from universities, WHO, the Brazilian Dermatological and Hansenology Societies and persons affected by leprosy gathered to kick off and commit their support to this multi-country, and multi-partner collaborative research programme. On 5 March (Sobral) and 6 March (Fortaleza) the first dose of a new preventive treatment was given to close contacts of persons affected by leprosy.